Gene:  GRID2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Human glutamate receptor delta-2 (GRID2) is a relatively new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. GRID2 is a predicted 1007 amino acid protein that shares 97% identity with the mouse homolog which is expressed selectively in cerebellar Purkinje cells. A point mutation in mouse GRID2 associated with the phenotype named 'lurcher' in the heterozygous state leads to ataxia resulting from selective cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This strongly suggests a role for GRID2 in neuronal apoptotic death. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: GRID2, Human
glutamate receptor, ionotropic, delta 2

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0002530
Info:   Same primer pair as used in probe assay qHsaCEP0024405
List Price:    $125.00
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PrimePCR™ Probe Assay: GRID2, Human
glutamate receptor, ionotropic, delta 2

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0024405
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: GRID2, Human
glutamate receptor, ionotropic, delta 2

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5001221
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0002530; Exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: GRID2, Human
glutamate receptor, ionotropic, delta 2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5026090
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0024405; Exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: GRID2, Human
glutamate receptor, ionotropic, delta 2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5026091
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0024405; Exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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