Gene:  GAD1, Human

print
PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

Why PrimePCR?

PrimePCR
Lookup Tool
Design and Validation of Real-Time PCR Primers
Pathway Curation
Control and Reference Assays for Real-Time PCR

This gene encodes one of several forms of glutamic acid decarboxylase identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq Jul 2008]

Select a product type :   All   qPCR   ddPCR
PrimePCR™ SYBR® Green Assay: GAD1, Human
glutamate decarboxylase 1 (brain, 67kDa)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0038024
Info:   Same primer pair as used in probe assay qHsaCIP0040747
List Price:   
Your Price:   Log In
Quantity:  
 
Add to Custom Plate
PrimePCR™ Probe Assay: GAD1, Human
glutamate decarboxylase 1 (brain, 67kDa)

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0040747
List Price:   
Your Price:   Log In
Quantity:  
 
PrimePCR™ ddPCR™ Mutation Assay:GAD1 p.R90C, Human
glutamate decarboxylase 1 (brain, 67kDa)

Assay Type: Probe
Application: In Silico Mutation Detection
Unique Assay ID: dHsaIS2504708
Info:   64nt amplicon; exonic; in-silico designed
 
Fluorophore:   FAM
List Price:   
Your Price:   Log In
Quantity:  
 
PrimePCR™ ddPCR™ Mutation Assay:GAD1 WT for p.R90C, Human
glutamate decarboxylase 1 (brain, 67kDa)

Assay Type: Probe
Application: In Silico Mutation Detection
Unique Assay ID: dHsaIS2504709
Info:   64nt amplicon; exonic; in-silico designed
 
Fluorophore:   HEX
List Price:   
Your Price:   Log In
Quantity:  
 
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
Get Help

Call us at 1-800-4-BIORAD (1-800-424-6723)

Sign Up for Bio-Rad Updates!
Enter your email address below to receive your choice of the latest news, promotions, and more.