Gene:  FXYD1, Human

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This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2 also known as the gamma subunit of the NaK-ATPase regulates the properties of that enzyme. FXYD1 (phospholemman) FXYD2 (gamma) FXYD3 (MAT-8) FXYD4 (CHIF) and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2) with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases including protein kinase A protein kinase C NIMA kinase and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity. Transcript variants with different 5' UTR sequences have been described in the literature. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: FXYD1, Human
FXYD domain containing ion transport regulator 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0020097
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: FXYD1, Human
FXYD domain containing ion transport regulator 1

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5023464
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0020097; Intron-spanning
List Price:    $125.00
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LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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