Gene:  FMO5, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme FMO1 found in fetal liver FMO2 found in adult liver and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs pesticides and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq Jan 2009]

PrimePCR™ SYBR® Green Assay: FMO5, Human
flavin containing monooxygenase 5

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0044408
Info:   Same primer pair as used in probe assay qHsaCEP0051670
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PrimePCR™ SYBR® Green Assay: FMO5, Human
flavin containing monooxygenase 5

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0011642
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PrimePCR™ Probe Assay: FMO5, Human
flavin containing monooxygenase 5

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0051670
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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