Gene:  FMO3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-sulfur- and phosphorous-containing xenobiotics such as therapeutic drugs dietary compounds pesticides and other foreign compounds. The human FMO gene family is composed of 5 genes and multiple pseudogenes. FMO members have distinct developmental- and tissue-specific expression patterns. The expression of this FMO3 gene the major FMO expressed in adult liver can vary up to 20-fold between individuals. This inter-individual variation in FMO3 expression levels is likely to have significant effects on the rate at which xenobiotics are metabolised and therefore is of considerable interest to the pharmaceutical industry. This transmembrane protein localizes to the endoplasmic reticulum of many tissues. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene cause the disorder trimethylaminuria (TMAu) which is characterized by the accumulation and excretion of unmetabolized trimethylamine and a distinctive body odor. In healthy individuals trimethylamine is primarily converted to the non odorous trimethylamine N-oxide.[provided by RefSeq Aug 2009]

Select a product type :   All   qPCR   ddPCR
PrimePCR™ SYBR® Green Assay: FMO3, Human
flavin containing monooxygenase 3

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0056971
Info:   Recommended - best efficiency; Same primer pair as used in probe assay qHsaCEP0058076
List Price:    $130.00
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PrimePCR™ SYBR® Green Assay: FMO3, Human
flavin containing monooxygenase 3

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0008817
List Price:    $130.00
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PrimePCR™ Probe Assay: FMO3, Human
flavin containing monooxygenase 3

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0058076
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: FMO3, Human
flavin containing monooxygenase 3

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5013559
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0056971; exonic
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: FMO3, Human
flavin containing monooxygenase 3

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5015929
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0008817; Intron-spanning
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression Probe Assay: FMO3, Human
flavin containing monooxygenase 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5045428
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0058076; exonic
 
Fluorophore:   FAM
List Price:    $195.00
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PrimePCR™ ddPCR™ Expression Probe Assay: FMO3, Human
flavin containing monooxygenase 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5045429
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0058076; exonic
 
Fluorophore:   HEX
List Price:    $195.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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