Gene:  Fance, Mouse

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes the complementation group E subunit of the multimeric Fanconi anemia (FA) nuclear complex composed of proteins encoded by over ten Fanconi anemia complementation (FANC) group genes: FANCA FANCB FANCC FANCD1 (also called BRCA2) FANCD2 FANCE FANCF FANCG FANCI FANCJ (also called BRIP1) FANCL FANCM and FANCN (also called PALB2). The FA complex is necessary for protection against DNA damage. This gene product is required for the nuclear accumulation of FANCC and provides a critical bridge between the FA complex and FANCD2. Defects in the related human gene are a cause of Fanconi anemia a genetically heterogeneous recessive disorder characterized by cytogenetic instability hypersensitivity to DNA crosslinking agents increased chromosomal breakage and defective DNA repair. Translation of this protein is initiated at a non-AUG (CUG) start codon which is inferred from the related human gene and the notion that this protein is functionally indispensable. Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq Aug 2009]

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PrimePCR™ SYBR® Green Assay: Fance, Mouse
Fanconi anemia, complementation group E

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qMmuCED0040791
Info:   Same primer pair as used in probe assay qMmuCEP0043008
List Price:    $125.00
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PrimePCR™ Probe Assay: Fance, Mouse
Fanconi anemia, complementation group E

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qMmuCEP0043008
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: Fance, Mouse
Fanconi anemia, complementation group E

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dMmuEG5064114
Info:   EG; Same primer pair as used in qPCR assay qMmuCED0040791; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: Fance, Mouse
Fanconi anemia, complementation group E

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dMmuCPE5091858
Info:   FAM; Same primer pair and probe as used in qPCR assay qMmuCEP0043008; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: Fance, Mouse
Fanconi anemia, complementation group E

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dMmuCPE5091859
Info:   HEX; Same primer pair and probe as used in qPCR assay qMmuCEP0043008; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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