Gene:  F13B, Human

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This gene encodes coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits which are identical to those of plasma origin. Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion the plasma factor XIII dissociates its B subunits and yields the same active enzyme factor XIIIa as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency characterized by the lack of both the A and B subunits; and type II deficiency characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency defective wound healing and habitual abortion. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: F13B, Human
coagulation factor XIII, B polypeptide

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0045109
Info:   Same primer pair as used in probe assay qHsaCEP0052370
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: F13B, Human
coagulation factor XIII, B polypeptide

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0009805
Info:   Recommended - best efficiency
List Price:    $125.00
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Add to Custom Plate
PrimePCR™ Probe Assay: F13B, Human
coagulation factor XIII, B polypeptide

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0052370
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: F13B, Human
coagulation factor XIII, B polypeptide

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5009681
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0045109; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: F13B, Human
coagulation factor XIII, B polypeptide

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5016645
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0009805; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: F13B, Human
coagulation factor XIII, B polypeptide

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5037672
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0052370; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: F13B, Human
coagulation factor XIII, B polypeptide

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5037673
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052370; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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