Gene:  DYRK1A, Human

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This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence a protein kinase domain a leucine zipper motif and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21 and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq Jul 2008]

Select a product type :   All   qPCR   ddPCR
PrimePCR™ SYBR® Green Assay: DYRK1A, Human
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0010296
Info:   Same primer pair as used in probe assay qHsaCIP0027525
List Price:    $125.00
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PrimePCR™ Probe Assay: DYRK1A, Human
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0027525
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: DYRK1A, Human
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5016988
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0010296; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Copy Number Assay: DYRK1A, Human
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000132
Info:   FAM: 70nt amplicon; crosses exon-intron junction
 
Fluorophore:   FAM
List Price:    $230.00
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PrimePCR™ ddPCR™ Copy Number Assay: DYRK1A, Human
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP2507028
Info:   HEX; 70nt amplicon; crosses exon-intron junction; HEX version of DYRK1A (dHsaCP1000132)
 
Fluorophore:   HEX
List Price:    $230.00
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PrimePCR™ ddPCR™ Expression Probe Assay: DYRK1A, Human
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5049110
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027525; Intron-spanning
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: DYRK1A, Human
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5049111
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0027525; Intron-spanning
 
Fluorophore:   HEX
List Price:    $190.00
Your Price:   Log In
Quantity:  
 
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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