Gene:  DUSP3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK SAPK/JNK p38) which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases different tissue distribution and subcellular localization and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues mutation screening in breast cancer pedigrees and in sporadic tumors was negative leading to the conclusion that this gene is not BRCA1. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: DUSP3, Human
dual specificity phosphatase 3

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0021960
Info:   Same primer pair as used in probe assay qHsaCIP0033251
List Price:    $125.00
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PrimePCR™ Probe Assay: DUSP3, Human
dual specificity phosphatase 3

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0033251
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: DUSP3, Human
dual specificity phosphatase 3

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5024241
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0021960; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: DUSP3, Human
dual specificity phosphatase 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5057754
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0033251; Intron-spanning
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: DUSP3, Human
dual specificity phosphatase 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5057755
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0033251; Intron-spanning
 
Fluorophore:   HEX
List Price:    $190.00
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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