Gene:  DOCK3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene is specifically expressed in the central nervous system (CNS). It encodes a member of the DOCK (dedicator of cytokinesis) family of guanine nucleotide exchange factors (GEFs). This protein dedicator of cytokinesis 3 (DOCK3) is also known as modifier of cell adhesion (MOCA) and presenilin-binding protein (PBP). The DOCK3 and DOCK1 -2 and -4 share several conserved amino acids in their DHR-2 (DOCK homology region 2) domains that are required for GEF activity and bind directly to WAVE proteins [Wiskott-Aldrich syndrome protein (WASP) family Verprolin-homologous proteins] via their DHR-1 domains. The DOCK3 induces axonal outgrowth in CNS by stimulating membrane recruitment of the WAVE complex and activating the small G protein Rac1. This gene is associated with an attention deficit hyperactivity disorder-like phenotype by a complex chromosomal rearrangement. [provided by RefSeq Aug 2010]

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PrimePCR™ SYBR® Green Assay: DOCK3, Human
dedicator of cytokinesis 3

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0016308
Info:   Same primer pair as used in probe assay qHsaCIP0030507
List Price:    $130.00
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PrimePCR™ Probe Assay: DOCK3, Human
dedicator of cytokinesis 3

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0030507
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: DOCK3, Human
dedicator of cytokinesis 3

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5021557
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0016308; Intron-spanning
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression Probe Assay: DOCK3, Human
dedicator of cytokinesis 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5054302
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0030507; Intron-spanning
 
Fluorophore:   FAM
List Price:    $195.00
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PrimePCR™ ddPCR™ Expression Probe Assay: DOCK3, Human
dedicator of cytokinesis 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5054303
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0030507; Intron-spanning
 
Fluorophore:   HEX
List Price:    $195.00
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Quantity:  
 
    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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