Gene:  DMP1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein which is critical for proper mineralization of bone and dentin is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains multiple phosphorylation sites a functional arg-gly-asp cell attachment sequence and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: DMP1, Human
dentin matrix acidic phosphoprotein 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0015301
Info:   Same primer pair as used in probe assay qHsaCIP0029841
List Price:    $125.00
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PrimePCR™ Probe Assay: DMP1, Human
dentin matrix acidic phosphoprotein 1

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0029841
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: DMP1, Human
dentin matrix acidic phosphoprotein 1

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5020707
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0015301; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: DMP1, Human
dentin matrix acidic phosphoprotein 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5053050
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0029841; Intron-spanning
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: DMP1, Human
dentin matrix acidic phosphoprotein 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5053051
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029841; Intron-spanning
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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