Gene:  Dclk2, Rat

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This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmoduline-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that this gene and the DCX gene, another family member, share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010]

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PrimePCR™ SYBR® Green Assay: Dclk2, Rat
Serine/threonine-protein kinase DCLK2

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qRnoCED0003205
List Price:    $134.00
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PrimePCR™ Probe Assay: Dclk2, Rat
Serine/threonine-protein kinase DCLK2

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qRnoCEP0025036
List Price:    $196.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: Dclk2, Rat
Serine/threonine-protein kinase DCLK2

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dRnoEG5125845
Info:   EG; Same primer pair as used in qPCR assay qRnoCED0003205; exonic
List Price:    $134.00
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PrimePCR™ ddPCR™ Expression Probe Assay: Dclk2, Rat
Serine/threonine-protein kinase DCLK2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dRnoCPE5147668
Info:   FAM; Same primer pair and probe as used in qPCR assay qRnoCEP0025036; exonic
 
Fluorophore:   FAM
List Price:    $201.00
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PrimePCR™ ddPCR™ Expression Probe Assay: Dclk2, Rat
Serine/threonine-protein kinase DCLK2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dRnoCPE5147669
Info:   HEX; Same primer pair and probe as used in qPCR assay qRnoCEP0025036; exonic
 
Fluorophore:   HEX
List Price:    $201.00
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6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download