Gene:  Dclk1, Rat

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This gene encodes a member of the protein kinase superfamily and the doublecortin family. The typical protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the protein is independent of its protein kinase activity. This gene is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been found, but the full-length nature of the variant produced from the 5' promoter has not been determined. Current reference sequence data represents two alternatively spliced transcript variants produced from the 3' promoter and their protein products lack the doublecortin domain.[provided by RefSeq, Sep 2010]

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PrimePCR™ SYBR® Green Assay: Dclk1, Rat
Serine/threonine-protein kinase DCLK1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qRnoCED0002033
List Price:    $125.00
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PrimePCR™ Probe Assay: Dclk1, Rat
Serine/threonine-protein kinase DCLK1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qRnoCEP0023864
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: Dclk1, Rat
Serine/threonine-protein kinase DCLK1

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dRnoEG5125406
Info:   EG; Same primer pair as used in qPCR assay qRnoCED0002033; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: Dclk1, Rat
Serine/threonine-protein kinase DCLK1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dRnoCPE5146790
Info:   FAM; Same primer pair and probe as used in qPCR assay qRnoCEP0023864; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: Dclk1, Rat
Serine/threonine-protein kinase DCLK1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dRnoCPE5146791
Info:   HEX; Same primer pair and probe as used in qPCR assay qRnoCEP0023864; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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