Gene:  CTNND2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome.[provided by RefSeq Aug 2010]

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PrimePCR™ SYBR® Green Assay: CTNND2, Human
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0001530
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PrimePCR™ SYBR® Green Assay: CTNND2, Human
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0046666
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0053927
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PrimePCR™ Probe Assay: CTNND2, Human
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0053927
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PrimePCR™ ddPCR™ Copy Number Assay: CTNND2, Human
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000533
Info:   64nt amplicon; crosses exon-intron junction
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay:CTNND2 p.I756I, Human
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)

Assay Type: Probe
Application: In Silico Mutation Detection
Unique Assay ID: dHsaIS2503702
Info:   65nt amplicon; crosses exon-intron junction; in-silico designed
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay:CTNND2 WT for p.I756I, Human
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)

Assay Type: Probe
Application: In Silico Mutation Detection
Unique Assay ID: dHsaIS2503703
Info:   65nt amplicon; crosses exon-intron junction; in-silico designed
 
Fluorophore:   HEX
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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