Gene:  COQ3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Ubiquinone also known as coenzyme Q or Q is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate 34-dihydroxy-5-polyprenylbenzoic acid as well as the final intermediate in the pathway converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM Mar 2008]

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PrimePCR™ SYBR® Green Assay: COQ3, Human
coenzyme Q3 homolog, methyltransferase (S. cerevisiae)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0018036
Info:   Same primer pair as used in probe assay qHsaCIP0031611
List Price:    $130.00
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PrimePCR™ Probe Assay: COQ3, Human
coenzyme Q3 homolog, methyltransferase (S. cerevisiae)

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0031611
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: COQ3, Human
coenzyme Q3 homolog, methyltransferase (S. cerevisiae)

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5189684
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0018036; Intron-spanning
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression Probe Assay: COQ3, Human
coenzyme Q3 homolog, methyltransferase (S. cerevisiae)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5192899
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031611; Intron-spanning
 
Fluorophore:   FAM
List Price:    $195.00
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PrimePCR™ ddPCR™ Expression Probe Assay: COQ3, Human
coenzyme Q3 homolog, methyltransferase (S. cerevisiae)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5192900
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0031611; Intron-spanning
 
Fluorophore:   HEX
List Price:    $195.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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