Gene:  COL11A2, Human

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This gene encodes one of the two alpha chains of type XI collagen a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome otospondylomegaepiphyseal dysplasia (OSMED syndrome) Weissenbacher-Zweymuller syndrome autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13) and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6. [provided by RefSeq Jul 2009]

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PrimePCR™ SYBR® Green Assay: COL11A2, Human
collagen, type XI, alpha 2

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0037290
Info:   Same primer pair as used in probe assay qHsaCEP0040013
List Price:    $125.00
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PrimePCR™ Probe Assay: COL11A2, Human
collagen, type XI, alpha 2

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0040013
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: COL11A2, Human
collagen, type XI, alpha 2

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5188441
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0037290; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: COL11A2, Human
collagen, type XI, alpha 2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5190573
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0040013; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: COL11A2, Human
collagen, type XI, alpha 2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5190574
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0040013; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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