Gene:  Cldn19, Mouse

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets and also play critical roles in maintaining cell polarity and signal transductions. siRNA knockdown of this gene in mice develops the FHHNC (familial hypomagnesemia with hypercalciuria and nephrocalcinosis) symptoms of chronic renal wasting of magnesium and calcium together with defective renal salt handling. The protein encoded by this gene interacts with another family member Claudin 16 and their interaction is required for their assembly into tight junctions and for renal reabsorption of magnesium. This protein is a constituent of tight junctions in the Schwann cells of peripheral myelinated nerves and the gene deficiency affects the nerve conduction of peripheral myelinated fibers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Aug 2010]

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PrimePCR™ SYBR® Green Assay: Cldn19, Mouse
Claudin 19

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qMmuCID0023540
Info:   Same primer pair as used in probe assay qMmuCIP0035726
List Price:    $125.00
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PrimePCR™ Probe Assay: Cldn19, Mouse
Claudin 19

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qMmuCIP0035726
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: Cldn19, Mouse
Claudin 19

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dMmuEG5085151
Info:   EG; Same primer pair as used in qPCR assay qMmuCID0023540; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: Cldn19, Mouse
Claudin 19

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dMmuCPE5122106
Info:   FAM; Same primer pair and probe as used in qPCR assay qMmuCIP0035726; Intron-spanning
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: Cldn19, Mouse
Claudin 19

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dMmuCPE5122107
Info:   HEX; Same primer pair and probe as used in qPCR assay qMmuCIP0035726; Intron-spanning
 
Fluorophore:   HEX
List Price:    $190.00
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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