Gene:  Cldn18, Mouse

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets and also play critical roles in maintaining cell polarity and signal transductions. This gene is a downstream target gene regulated by the T/EBP/NKX2.1 homeodomain transcription factor. Four alternatively spliced transcript variants resulted from alternative promoters and alternative splicing have been identified which encode two lung-specific isoforms and two stomach-specific isoforms respectively. This gene is also expressed in colons inner ear and skin and its expression is increased in both experimental colitis and ulcerative colitis. [provided by RefSeq Aug 2010]

PrimePCR™ SYBR® Green Assay: Cldn18, Mouse
Claudin 18

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qMmuCED0047629
Info:   Recommended - best coverage; Same primer pair as used in probe assay qMmuCEP0056055
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PrimePCR™ SYBR® Green Assay: Cldn18, Mouse
Claudin 18

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qMmuCID0025525
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PrimePCR™ Probe Assay: Cldn18, Mouse
Claudin 18

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qMmuCEP0056055
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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