Gene:  CILP, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Major alterations in the composition of the cartilage extracellular matrix occur in joint disease such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP) which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase however later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease. [provided by RefSeq Sep 2010]

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PrimePCR™ SYBR® Green Assay: CILP, Human
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0016987
Info:   Same primer pair as used in probe assay qHsaCIP0030943
List Price:    $125.00
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PrimePCR™ Probe Assay: CILP, Human
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0030943
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CILP, Human
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5022142
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0016987; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CILP, Human
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5055128
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0030943; Intron-spanning
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CILP, Human
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5055129
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0030943; Intron-spanning
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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