Gene:  CHRFAM7A, Human

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The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7 which is located on chromosome 15 in a region associated with several neuropsychiatric disorders is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed and two variants exist for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: CHRFAM7A, Human
CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0020006
List Price:    $125.00
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Add to Custom Plate
PrimePCR™ SYBR® Green Assay: CHRFAM7A, Human
CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0046398
Info:   Same primer pair as used in probe assay qHsaCEP0053659
List Price:    $125.00
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Add to Custom Plate
PrimePCR™ Probe Assay: CHRFAM7A, Human
CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0053659
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CHRFAM7A, Human
CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5004684
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0020006; Exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CHRFAM7A, Human
CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5189191
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0046398; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CHRFAM7A, Human
CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5192073
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0053659; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CHRFAM7A, Human
CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5192074
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053659; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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