Gene:  CHMP4B, Human

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This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III) which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP also known as ALIX) which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.[provided by RefSeq Oct 2009]

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PrimePCR™ SYBR® Green Assay: CHMP4B, Human
chromatin modifying protein 4B

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0003188
List Price:    $130.00
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PrimePCR™ SYBR® Green Assay: CHMP4B, Human
chromatin modifying protein 4B

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0042867
Info:   Same primer pair as used in probe assay qHsaCEP0050129
List Price:    $130.00
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Add to Custom Plate
PrimePCR™ Probe Assay: CHMP4B, Human
chromatin modifying protein 4B

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0050129
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CHMP4B, Human
chromatin modifying protein 4B

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5001709
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0003188; Exonic
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CHMP4B, Human
chromatin modifying protein 4B

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5007708
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0042867; exonic
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CHMP4B, Human
chromatin modifying protein 4B

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5033728
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0050129; exonic
 
Fluorophore:   FAM
List Price:    $195.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CHMP4B, Human
chromatin modifying protein 4B

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5033729
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0050129; exonic
 
Fluorophore:   HEX
List Price:    $195.00
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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