Gene:  CHM, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid retinal pigment epithelium and retina. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq Feb 2009]

Select a product type :   All   qPCR   ddPCR
PrimePCR™ SYBR® Green Assay: CHM, Human
choroideremia (Rab escort protein 1)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0047975
Info:   Same primer pair as used in probe assay qHsaCEP0055235
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: CHM, Human
choroideremia (Rab escort protein 1)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0012100
List Price:    $125.00
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PrimePCR™ Probe Assay: CHM, Human
choroideremia (Rab escort protein 1)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0055235
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CHM, Human
choroideremia (Rab escort protein 1)

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5012250
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0047975; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CHM, Human
choroideremia (Rab escort protein 1)

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5018398
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0012100; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CHM, Human
choroideremia (Rab escort protein 1)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5042810
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0055235; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CHM, Human
choroideremia (Rab escort protein 1)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5042811
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0055235; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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