Gene:  CEP57, Human

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This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization and the C-terminal half is required for nucleating bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2) sorting nexin 6 Ran-binding protein M and the kinesins KIF3A and KIF3B and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome a rare autosomal recessive disorder. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Aug 2011]

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PrimePCR™ SYBR® Green Assay: CEP57, Human
centrosomal protein 57kDa

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0046347
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0053608
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: CEP57, Human
centrosomal protein 57kDa

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0009243
List Price:    $125.00
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PrimePCR™ Probe Assay: CEP57, Human
centrosomal protein 57kDa

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0053608
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CEP57, Human
centrosomal protein 57kDa

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5010798
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0046347; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CEP57, Human
centrosomal protein 57kDa

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5016244
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0009243; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CEP57, Human
centrosomal protein 57kDa

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5039906
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0053608; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CEP57, Human
centrosomal protein 57kDa

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5039907
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053608; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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