Gene:  CACNB4, Human

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This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1 alpha-2/delta beta and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition increasing peak calcium current controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Mar 2009]

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PrimePCR™ SYBR® Green Assay: CACNB4, Human
calcium channel, voltage-dependent, beta 4 subunit

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0047528
Info:   Same primer pair as used in probe assay qHsaCEP0054788
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: CACNB4, Human
calcium channel, voltage-dependent, beta 4 subunit

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0021708
Info:   Recommended - best coverage
List Price:    $125.00
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PrimePCR™ Probe Assay: CACNB4, Human
calcium channel, voltage-dependent, beta 4 subunit

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0054788
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CACNB4, Human
calcium channel, voltage-dependent, beta 4 subunit

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5011855
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0047528; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CACNB4, Human
calcium channel, voltage-dependent, beta 4 subunit

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5189762
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0021708; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CACNB4, Human
calcium channel, voltage-dependent, beta 4 subunit

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5042020
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0054788; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CACNB4, Human
calcium channel, voltage-dependent, beta 4 subunit

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5042021
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0054788; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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