Gene:  BRCA2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Inherited mutations in BRCA1 and this gene BRCA2 confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq Dec 2008]

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PrimePCR™ SYBR® Green Assay: BRCA2, Human
breast cancer 2, early onset

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0023857
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: BRCA2, Human
breast cancer 2, early onset

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0044922
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0052184
List Price:    $125.00
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Add to Custom Plate
PrimePCR™ Probe Assay: BRCA2, Human
breast cancer 2, early onset

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0052184
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: BRCA2, Human
breast cancer 2, early onset

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5005142
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0023857; Exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: BRCA2, Human
breast cancer 2, early onset

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5009522
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0044922; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Copy Number Assay: BRCA2, Human
breast cancer 2, early onset

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000009
Info:   FAM: 119nt amplicon; intronic
 
Fluorophore:   FAM
List Price:    $230.00
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PrimePCR™ ddPCR™ Copy Number Assay: BRCA2, Human
breast cancer 2, early onset

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP2500368
Info:   FAM; 70nt amplicon; exonic; FAM version of BRCA2 (dHsaCP2506545)
 
Fluorophore:   FAM
List Price:    $230.00
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PrimePCR™ ddPCR™ Copy Number Assay: BRCA2, Human
breast cancer 2, early onset

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP2506545
Info:   HEX; 70nt amplicon; exonic; HEX version of BRCA2 (dHsaCP2500368)
 
Fluorophore:   HEX
List Price:    $230.00
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PrimePCR™ ddPCR™ Copy Number Assay: BRCA2, Human
breast cancer 2, early onset

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP2506980
Info:   HEX; 119nt amplicon; intronic; HEX version of BRCA2 (dHsaCP1000009)
 
Fluorophore:   HEX
List Price:    $230.00
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PrimePCR™ ddPCR™ Expression Probe Assay: BRCA2, Human
breast cancer 2, early onset

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5037356
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0052184; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: BRCA2, Human
breast cancer 2, early onset

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5037357
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052184; exonic
 
Fluorophore:   HEX
List Price:    $190.00
Your Price:   Log In
Quantity:  
 
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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