Gene:  BMPR1A, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors but they require their respective type I receptors for signaling whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: BMPR1A, Human
bone morphogenetic protein receptor, type IA

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0003308
Info:   Same primer pair as used in probe assay qHsaCEP0024658
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PrimePCR™ Probe Assay: BMPR1A, Human
bone morphogenetic protein receptor, type IA

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0024658
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PrimePCR™ ddPCR™ Mutation Assay:BMPR1A p.R486L, Human
bone morphogenetic protein receptor, type IA

Assay Type: Probe
Application: In Silico Mutation Detection
Unique Assay ID: dHsaIS2503012
Info:   70nt amplicon; crosses exon-intron junction; in-silico designed
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay:BMPR1A WT for p.R486L, Human
bone morphogenetic protein receptor, type IA

Assay Type: Probe
Application: In Silico Mutation Detection
Unique Assay ID: dHsaIS2503013
Info:   70nt amplicon; crosses exon-intron junction; in-silico designed
 
Fluorophore:   HEX
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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