Gene:  BEST1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2) also known as Best macular dystrophy in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq Nov 2008]

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PrimePCR™ SYBR® Green Assay: BEST1, Human
bestrophin 1

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0002376
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: BEST1, Human
bestrophin 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0046514
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0053775
List Price:    $125.00
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Add to Custom Plate
PrimePCR™ Probe Assay: BEST1, Human
bestrophin 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0053775
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: BEST1, Human
bestrophin 1

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5001097
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0002376; Exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: BEST1, Human
bestrophin 1

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5010948
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0046514; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: BEST1, Human
bestrophin 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5040206
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0053775; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: BEST1, Human
bestrophin 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5040207
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053775; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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