Gene:  BCL10, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD) and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9 10 11 and 14 which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1 a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: BCL10, Human
B-cell CLL/lymphoma 10

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0009788
Info:   Same primer pair as used in probe assay qHsaCIP0027324
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PrimePCR™ Probe Assay: BCL10, Human
B-cell CLL/lymphoma 10

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0027324
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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