Gene:  BAI1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Design and Validation of Real-Time PCR Primers
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Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: BAI1, Human
brain-specific angiogenesis inhibitor 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0018375
Info:   Same primer pair as used in probe assay qHsaCIP0031816
List Price:    $125.00
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PrimePCR™ Probe Assay: BAI1, Human
brain-specific angiogenesis inhibitor 1

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0031816
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: BAI1, Human
brain-specific angiogenesis inhibitor 1

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5023206
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0018375; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: BAI1, Human
brain-specific angiogenesis inhibitor 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5056696
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031816; Intron-spanning
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: BAI1, Human
brain-specific angiogenesis inhibitor 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5056697
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0031816; Intron-spanning
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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