Gene:  BAG4, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2 Raf-protein kinase steroid hormone receptors growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3) and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq Mar 2011]

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PrimePCR™ SYBR® Green Assay: BAG4, Human
BCL2-associated athanogene 4

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0038849
Info:   Same primer pair as used in probe assay qHsaCEP0041571
List Price:    $125.00
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PrimePCR™ Probe Assay: BAG4, Human
BCL2-associated athanogene 4

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0041571
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: BAG4, Human
BCL2-associated athanogene 4

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5006706
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038849; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: BAG4, Human
BCL2-associated athanogene 4

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5031724
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0041571; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: BAG4, Human
BCL2-associated athanogene 4

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5031725
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0041571; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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