Gene:  ATXN2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum brain stem and spinal cord. Clinically ADCA has been divided into three groups: ADCA types I-III. Defects in this gene are the cause of spinocerebellar ataxia type 2 (SCA2). SCA2 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy ophthalmoplegia bulbar and extrapyramidal signs peripheral neuropathy and dementia. SCA2 is caused by expansion of a CAG repeat in the coding region of this gene. This locus has been mapped to chromosome 12 and it has been determined that the diseased allele contains 37-50 CAG repeats compared to 17-29 in the normal allele. Longer expansions result in earlier onset of the disease. Alternatively spliced transcript variants encoding different isoforms have been identified but their full length sequence has not been determined. [provided by RefSeq Jan 2010]

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PrimePCR™ SYBR® Green Assay: ATXN2, Human
ataxin 2

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0001707
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: ATXN2, Human
ataxin 2

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0048465
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0055725
List Price:    $125.00
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Add to Custom Plate
PrimePCR™ Probe Assay: ATXN2, Human
ataxin 2

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0055725
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ATXN2, Human
ataxin 2

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5000573
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0001707; Exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ATXN2, Human
ataxin 2

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5012686
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0048465; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: ATXN2, Human
ataxin 2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5043682
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0055725; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: ATXN2, Human
ataxin 2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5043683
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0055725; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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