Gene:  ARNTL, Cow

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The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2014]

PrimePCR™ SYBR® Green Assay: ARNTL, Cow
Aryl hydrocarbon receptor nuclear translocator-like

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qBtaCID0002566
List Price:    $102.00
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PrimePCR™ Probe Assay: ARNTL, Cow
Aryl hydrocarbon receptor nuclear translocator-like

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qBtaCIP0022328
List Price:    $196.00
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    Related pathways not available
Number Description Download
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LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download