Gene:  ALOXE3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene is a member of the lipoxygenase family which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R12R-epoxyeicosa-5Z9E14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha) which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq Sep 2009]

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PrimePCR™ SYBR® Green Assay: ALOXE3, Human
arachidonate lipoxygenase 3

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0017551
Info:   Same primer pair as used in probe assay qHsaCIP0031320
List Price:    $125.00
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PrimePCR™ Probe Assay: ALOXE3, Human
arachidonate lipoxygenase 3

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0031320
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ALOXE3, Human
arachidonate lipoxygenase 3

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5022603
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0017551; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: ALOXE3, Human
arachidonate lipoxygenase 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5055836
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031320; Intron-spanning
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: ALOXE3, Human
arachidonate lipoxygenase 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5055837
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0031320; Intron-spanning
 
Fluorophore:   HEX
List Price:    $190.00
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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