Gene:  ALDH18A1, Human

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This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate a critical step in the de novo biosynthesis of proline ornithine and arginine. Mutations in this gene lead to hyperammonemia hypoornithinemia hypocitrullinemia hypoargininemia and hypoprolinemia and may be associated with neurodegeneration cataracts and connective tissue diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: ALDH18A1, Human
aldehyde dehydrogenase 18 family, member A1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0042176
Info:   Same primer pair as used in probe assay qHsaCEP0049439
List Price:    $130.00
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PrimePCR™ SYBR® Green Assay: ALDH18A1, Human
aldehyde dehydrogenase 18 family, member A1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0018462
List Price:    $130.00
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PrimePCR™ Probe Assay: ALDH18A1, Human
aldehyde dehydrogenase 18 family, member A1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0049439
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ALDH18A1, Human
aldehyde dehydrogenase 18 family, member A1

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5007133
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0042176; exonic
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ALDH18A1, Human
aldehyde dehydrogenase 18 family, member A1

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5023274
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0018462; Intron-spanning
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression Probe Assay: ALDH18A1, Human
aldehyde dehydrogenase 18 family, member A1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5032578
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0049439; exonic
 
Fluorophore:   FAM
List Price:    $195.00
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PrimePCR™ ddPCR™ Expression Probe Assay: ALDH18A1, Human
aldehyde dehydrogenase 18 family, member A1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5032579
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0049439; exonic
 
Fluorophore:   HEX
List Price:    $195.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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