Gene:  AKAP13, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in at least 3 transcript variants encoding different isoforms containing a dbl oncogene homology (DH) domain and a pleckstrin homology (PH) domain. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway and in addition function as protein kinase A-anchoring proteins. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: AKAP13, Human
A kinase (PRKA) anchor protein 13

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0056553
Info:   Same primer pair as used in probe assay qHsaCEP0057658
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PrimePCR™ SYBR® Green Assay: AKAP13, Human
A kinase (PRKA) anchor protein 13

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0017532
Info:   Recommended - best coverage
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PrimePCR™ Probe Assay: AKAP13, Human
A kinase (PRKA) anchor protein 13

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0057658
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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