Gene:  ADD2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

Why PrimePCR?

PrimePCR
Lookup Tool
Design and Validation of Real-Time PCR Primers-test
Pathway Curation
and Array Design Strategy
Control and Reference Assays for Real-Time PCR

Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin originally purified from human erythrocytes was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C the binding site for calmodulin and is required for association with spectrin and actin. Alternatively spliced transcript variants have been described. [provided by RefSeq Jun 2010]

PrimePCR™ SYBR® Green Assay: ADD2, Human
adducin 2 (beta)

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0007800
Info:   Same primer pair as used in probe assay qHsaCEP0025665
List Price:    $174.00
Your Price:   Log In
Quantity:  
 
Add to Custom Plate
PrimePCR™ Probe Assay: ADD2, Human
adducin 2 (beta)

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0025665
List Price:    $255.00
Your Price:   Log In
Quantity:  
 
Number Description Download
10000143205 SARS-CoV-2 Variant Detection RT-PCR Assay Protocol Click to download
3226 PIS_PrimePCR SARS-CoV-2 Single and Multiple Mutation Assays Click to download
10000147102 PrimePCR SARS-CoV-2 Multiple Mutation Assay Protocol Click to download