Gene:  ADAMTS4, Human

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This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules including a propeptide region a metalloproteinase domain a disintegrin-like domain and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan a major proteoglycan of cartilage and brevican a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system potentially in the progression of glioma. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: ADAMTS4, Human
ADAM metallopeptidase with thrombospondin type 1 motif, 4

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0004386
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PrimePCR™ SYBR® Green Assay: ADAMTS4, Human
ADAM metallopeptidase with thrombospondin type 1 motif, 4

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0057195
Info:   Same primer pair as used in probe assay qHsaCEP0058300
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PrimePCR™ Probe Assay: ADAMTS4, Human
ADAM metallopeptidase with thrombospondin type 1 motif, 4

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0058300
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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