Gene:  ADAMTS13, Human

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This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules including a propeptide region a metalloproteinase domain a disintegrin-like domain and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq Nov 2008]

PrimePCR™ SYBR® Green Assay: ADAMTS13, Human
ADAM metallopeptidase with thrombospondin type 1 motif, 13

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0038726
Info:   Same primer pair as used in probe assay qHsaCIP0041448
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PrimePCR™ Probe Assay: ADAMTS13, Human
ADAM metallopeptidase with thrombospondin type 1 motif, 13

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0041448
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    Related pathways not available
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