PrimePCR™ lncRNA® Probe Assay:SIM2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   Same primer pair as used in SYBR assay qhsaLID0134159

List Price:    $247.00
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PrimePCR™ IncRNA PreAmp for Probe Assay: SIM2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ IncRNA Template for Probe Assay: SIM2, Human
Reaction:     4 billion copies/200 µl
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   lncRNA Expression
Unique Assay ID:   qhsaLIP0211399
Assay Design:   intron_spanning
Chromosome Location:   chr21:36712582-36719886question
Amplicon Length:   77
Splice Variants Targeted:   ENST00000483178 ENST00000431229 ENST00000290399 ENST00000481185
LNCipedia Splice Variants Targeted:   lnc-DSCR6-7:1

Gene Information

SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. The Drosophila sim gene encodes a transcription factor that is a master regulator of fruit fly neurogenesis. SIM2 maps within the so-called Down syndrome chromosomal region. Based on the mapping position its potential function as transcriptional repressor and similarity to Drosophila sim it is proposed that SIM2 may contribute to some specific Down syndrome phenotypes [provided by RefSeq Jul 2008]

Gene Symbol:   SIM2
Gene Name:   single-minded homolog 2 (Drosophila)
Aliases:   MGC119447, SIM, bHLHe15
RefSeq:   NC_000021.8 NG_016193.1 NT_011512.11
Ensembl:   ENSG00000159263
LNCipedia:   lnc-DSCR6-7
Entrez:   6493
Chromosome Mapping:   21q22.2,21q22.13
Gene Strand:   Not Available

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