PrimePCR™ lncRNA® Probe Assay:UPF2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   Same primer pair as used in SYBR assay qhsaLED0104469

List Price:    $247.00
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PrimePCR™ IncRNA PreAmp for Probe Assay: UPF2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ IncRNA Template for Probe Assay: UPF2, Human
Reaction:     4 billion copies/200 µl
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   lncRNA Expression
Unique Assay ID:   qhsaLEP0181709
Assay Design:   exonic
Chromosome Location:   chr10:12035116-12035254question
Amplicon Length:   109
Refseq Transcripts Amplified:   NM_080599,NM_015542,XM_011519449,XR_930489
Splice Variants Targeted:   ENST00000356352 ENST00000357604 ENST00000397053 ENST00000460569
LNCipedia Splice Variants Targeted:   lnc-NUDT5-3:1

Gene Information

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq Jul 2008]

Gene Symbol:   UPF2
Gene Name:   UPF2 regulator of nonsense transcripts homolog (yeast)
Aliases:   DKFZp434D222, HUPF2, KIAA1408, MGC138834, MGC138835, RENT2, smg-3
RefSeq:   NC_000010.10 NT_008705.16
Ensembl:   ENSG00000151461
LNCipedia:   lnc-NUDT5-3
Entrez:   26019
Chromosome Mapping:   10p14-p13
Gene Strand:   Not Available

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