PrimePCR™ lncRNA® Probe Assay:LAMTOR3, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   Same primer pair as used in SYBR assay qhsaLED0103778

List Price:    $247.00
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PrimePCR™ IncRNA PreAmp for Probe Assay: LAMTOR3, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ IncRNA Template for Probe Assay: LAMTOR3, Human
Reaction:     4 billion copies/200 µl
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   lncRNA Expression
Unique Assay ID:   qhsaLEP0181018
Assay Design:   exonic
Chromosome Location:   chr4:99881614-99881735question
Amplicon Length:   92
Refseq Transcripts Amplified:   NM_001243736,NM_021970,NR_024170
Splice Variants Targeted:   ENST00000499666 ENST00000515100 ENST00000226522
LNCipedia Splice Variants Targeted:   lnc-LAMTOR3-1:1

Gene Information

This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein and binds specifically to MAP kinase kinase MAP2K1/MEK1 MAP kinase MAPK3/ERK1 and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq Aug 2011]

Gene Symbol:   LAMTOR3
Gene Name:   late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Aliases:   MAP2K1IP1, MAPBP, MAPKSP1, MP1, Ragulator3
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000109270
LNCipedia:   lnc-LAMTOR3-1
Entrez:   8649
Chromosome Mapping:   4q23
Gene Strand:   Not Available

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