PrimePCR™ lncRNA® Probe Assay:NOD2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   Same primer pair as used in SYBR assay qhsaLED0103426

List Price:    $247.00
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PrimePCR™ IncRNA PreAmp for Probe Assay: NOD2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ IncRNA Template for Probe Assay: NOD2, Human
Reaction:     4 billion copies/200 µl
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   lncRNA Expression
Unique Assay ID:   qhsaLEP0180666
Assay Design:   exonic
Chromosome Location:   chr16:50712205-50712352question
Amplicon Length:   118
Splice Variants Targeted:   ENST00000529633 ENST00000527052 ENST00000534067 ENST00000300589 ENST00000534057 ENST00000524712
LNCipedia Splice Variants Targeted:   lnc-CYLD-2:2 lnc-CYLD-2:1 lnc-CYLD-2:3 lnc-CYLD-2:4

Gene Information

This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq Jul 2008]

Gene Symbol:   NOD2
Gene Name:   nucleotide-binding oligomerization domain containing 2
Aliases:   ACUG, BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1
RefSeq:   NC_000016.9 NG_007508.1 NT_010498.15
Ensembl:   ENSG00000167207
LNCipedia:   lnc-CYLD-2
Entrez:   64127
Chromosome Mapping:   16q21
Gene Strand:   Not Available

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