PrimePCR™ lncRNA® Probe Assay:IL18BP, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   Same primer pair as used in SYBR assay qhsaLED0103218

List Price:    $247.00
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PrimePCR™ IncRNA PreAmp for Probe Assay: IL18BP, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ IncRNA Template for Probe Assay: IL18BP, Human
Reaction:     4 billion copies/200 µl
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   lncRNA Expression
Unique Assay ID:   qhsaLEP0180458
Assay Design:   exonic
Chromosome Location:   chr11:72002310-72002411question
Amplicon Length:   72
Splice Variants Targeted:   ENST00000337131 ENST00000393705 ENST00000393707 ENST00000343898 ENST00000620017 ENST00000497194 ENST00000404792 ENST00000393703 ENST00000260049
LNCipedia Splice Variants Targeted:   lnc-RNF121-2:1

Gene Information

The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine IL18. It binds IL18 prevents the binding of IL18 to its receptor and thus inhibits IL18-induced IFN-gamma production resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq Feb 2011]

Gene Symbol:   IL18BP
Gene Name:   interleukin 18 binding protein
Aliases:   IL18BPa
RefSeq:   NC_000011.9 NT_167190.1
Ensembl:   ENSG00000137496
LNCipedia:   lnc-RNF121-2
Entrez:   10068
Chromosome Mapping:   11q13
Gene Strand:   Not Available

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