This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
PrimePCR™ PreAmp for Probe Assay: CDKN2B, Chicken
PrimePCR™ Template for Probe Assay: CDKN2B, Chicken
This gene encodes a protein similar to one of two mammalian cyclin-dependent kinase inhibitor proteins which regulate the activity of cyclin-dependent protein kinases CDK4 and CDK6 which further cell cycle progression through G1. Expression of this protein in human keratinocytes is induced by TGF-beta, a cytokine that inhibits cell growth through arrest in the G1 phase of the cell cycle. There is evidence that the encoded protein is functionally equivalent to mammalian p16INK4a, a protein from a similar but distinct mammalian gene. [provided by RefSeq, Dec 2008]