PrimePCR™ Probe Assay: CLOCK, Cow

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $255.00
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PrimePCR™ PreAmp for Probe Assay: CLOCK, Cow
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: CLOCK, Cow
Reaction:     4 billion copies/200 µl
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qBtaCIP0025240
Assay Design:   Intron-spanning
Chromosome Location:   6:72589524-72596967question
Amplicon Length:   104
Splice Variants Targeted:   ENSBTAT00000061480

Gene Information

The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. [provided by RefSeq, Feb 2014]

Gene Symbol:   CLOCK
Gene Name:   Clock circadian regulator
Aliases:   Not Available
RefSeq:   XM_005207981 XM_002688257 XM_005207980 XM_005207983 XM_005207982 XM_005207984
Ensembl:   ENSBTAG00000044044
Entrez:   100300400
Chromosome Mapping:   6

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