PrimePCR™ ddPCR™ Expression Probe Assay: Clock, Rat


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qRnoCIP0031058; intron_spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dRnoCPE5176404
Chromosome Location:   14:34268432-34271899question
Amplicon Length:   112

Gene Information

The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with Arntl (Bmal1) that binds E-box enhancer elements upstream of Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2) genes and activates transcription of these genes. Per and Cry proteins heterodimerize and repress their own transcription by interacting in a feedback loop with Clock/Arntl complexes. Polymorphisms in this gene may be associated with behavioral changes, obesity, and metabolic syndrome. Two transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014]

Gene Symbol:   Clock
Gene Name:   Circadian locomoter output cycles protein kaput
Aliases:   Not Available
RefSeq:   Not Available
Ensembl:   ENSRNOG00000002175
Entrez:   60447
UniGene:   Rn.205839
Chromosome Mapping:   14p11

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