PrimePCR™ ddPCR™ Expression Probe Assay: Hap1, Rat

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qRnoCIP0030270; intron_spanning

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dRnoCPE5175505
Chromosome Location:   10:88055547-88056922question
Amplicon Length:   110

Gene Information

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that is homologous to the human huntingtin-associated protein 1. The human protein interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Two transcripts encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Gene Symbol:   Hap1
Gene Name:   Huntingtin-associated protein 1 isoform B
Aliases:   Not Available
RefSeq:   NM_177982 NM_024133
Ensembl:   ENSRNOG00000014819
Entrez:   29430
UniGene:   Rn.37430
Chromosome Mapping:   10q32.1

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