PrimePCR™ ddPCR™ Expression Probe Assay: Htr2c, Rat

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qRnoCEP0045651; Exonic

 
Fluorophore:   HEX
List Price:    $207.00
Your Price:   Log In
 

Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dRnoCPE5165657
Chromosome Location:   X:118458574-118458703question
Amplicon Length:   100

Gene Information

Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in rodents show altered patterns of RNA editing in response to drug treatments and stressful situations. [provided by RefSeq, Jul 2008]

Gene Symbol:   Htr2c
Gene Name:   5-hydroxytryptamine receptor 2C
Aliases:   Not Available
RefSeq:   NM_012765
Ensembl:   ENSRNOG00000030877
Entrez:   25187
UniGene:   Rn.9935
Chromosome Mapping:   Xq34-q35.1

Number Description Download