PrimePCR™ ddPCR™ Expression EvaGreen® Assay: Dcx, Mouse

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qMmuCID0010580; Intron-spanning

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dMmuEG5076312
Chromosome Location:   X:143923345-143930979question
Amplicon Length:   94

Gene Information

This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains which bind microtubules. In the developing cortex cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition the encoded protein interacts with LIS1 the regulatory gamma subunit of platelet activating factor acetylhydrolase. Studies in knockout mice lacking this gene and the LIS1 gene suggest that the molecular interaction of these two genes is important in both in neuronal migration and neurogenesis and there is a cortical role of this gene in nuclear translocation and positioning of the mitotic spindle in radial glial mitotic division. Multiple transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq Sep 2010]

Gene Symbol:   Dcx
Gene Name:   Doublecortin
Aliases:   Dbct
RefSeq:   NC_000086.7 NT_039718.8
Ensembl:   ENSMUSG00000031285
Entrez:   13193
UniGene:   Mm.12871
Chromosome Mapping:   X F2|X

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