PrimePCR™ ddPCR™ Expression EvaGreen® Assay: Myc, Mouse

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qMmuCID0006528; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dMmuEG5073598
Chromosome Location:   15:61988224-61989409question
Amplicon Length:   89

Gene Information

The protein encoded by this gene is a multifunctional nuclear phosphoprotein that plays a role in cell cycle progression apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations overexpression rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors leukemias and lymphomas including Burkitt lymphoma in human. There is evidence to show that alternative translation initiations from an upstream in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini in human and mouse. Under conditions of stress such as high cell densities and methionine deprivation there is a specific and dramatic increase in the synthesis of the non-AUG initiated protein suggesting its importance in times of adversity. Alternative splicing results in multiple transcript variants. [provided by RefSeq Apr 2010]

Gene Symbol:   Myc
Gene Name:   Myelocytomatosis oncogene
Aliases:   AU016757, Myc2, Niard, Nird, bHLHe39
RefSeq:   NC_000081.6 NT_039621.8
Ensembl:   ENSMUSG00000022346
Entrez:   17869
UniGene:   Mm.2444
Chromosome Mapping:   15 D2-D3|15 32.0 cM

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